ncRNA name | hsa-miR-124 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cells; RB cell lines Y79, WERI-RB1, SO-Rb50 and HXO-RB45 |
Methods | transfection, luciferase reporter assay, Western blot, qRT-PCR, autophagy assay |
Expression pattern | down-regulated |
Functional description | miR-124 regulates autophagy flux and could act as potent inhibitor of starvation-induced autophagy in Y79 cells. STX17 was involved in miR-124 regulation of retinoblastoma cell autophagy through miR-124 direct binding to the 3’UTR of STX17. |
PubMed ID | 29073720 |
Year | 2018 |
Title | MALAT1 modulates the autophagy of retinoblastoma cell through miR-124-mediated stx17 regulation. |
Drug-related ncRNA | NO |
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